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According to the study

This Factor Increases Dementia Risk in Men–But Not in Women

Can the Death of a Wife Increase Her Husband's Risk of Dementia?
The death of a partner is a traumatic event, but how does it affect the long-term health of older adults? Photo: Getty Images
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March 17, 2026, 4:01 pm | Read time: 6 minutes

The death of a wife increases the risk of dementia in older men, according to a recent study from Japan. Women, on the other hand, often fare better after the mourning period. How can this be explained?

The loss of a spouse is one of the most stressful life events. Especially older couples must prepare for the fact that one of them will eventually pass away first. When that time comes, the well-being of the surviving partner usually suffers. But how much does widowhood really affect health? Are there differences between men and women? And can time still heal wounds later in life? A research team from the Boston University School of Public Health and Chiba University in Japan sought to answer these questions. The results of the study, published in the Journal of Affective Disorders, are particularly concerning for men.1 The death of a wife can literally drive them to madness.

Study with Nearly 26,000 Japanese Women and Men Over 65

For their analysis, the team used data from the Japanese Gerontological Evaluation Study, a large-scale study of Japanese seniors aged 65 and older. The researchers focused on the years 2013, 2016, and 2019, initially asking participants the following questions:

  • Is the person currently married?
  • Or now widowed?
  • When did the partner die?

During this period, 1,076 participants experienced the death of their spouse. They were asked 37 health-related questions connected to the loss, including the severity of grief, (unhealthy) coping strategies such as alcohol consumption, feelings of loneliness, and clinical diagnoses like depression or dementia.

At the same time, the researchers examined whether physical and mental well-being had improved or worsened three and six years later. They also investigated whether the surviving partner had died in the meantime. After dividing the results by gender, an intriguing picture emerged.

Dementia, Depression, Isolation–How Harmful the Death of a Wife Is for Men

The gender-specific differences proved to be enormous. Compared to non-widowed men, those who had lost their partner showed a higher risk of dementia. Their life satisfaction generally decreased significantly, followed by hopelessness, which in turn led to increased alcohol consumption. The resulting mental and physical decline increased mortality. Generally, the period three to six months after the loss is considered particularly critical–earlier studies have already provided evidence for this.2

This means: The death of their wives shortens the life expectancy of Japanese men. Improvement is possible, but it only occurs gradually and is a lengthy process.

Happy Widows

Women, on the other hand, seemed to cope better with the death of their husbands. Although they initially suffered from the loss, their joy for life quickly returned after the mourning period. The researchers also found no increased risk of dementia or depression. On the contrary, many Japanese widows reported improved well-being that continued to increase. How can this be explained? After all, the women and men studied reacted similarly to the death of their spouse by initially trying to become more socially active. This included meeting with friends and family, participating in neighborhood activities, or volunteering. Men found this comparatively difficult. While women found genuine support through new contacts, men often still felt alone despite the activities–the social network provided them with less emotional support.

The Underestimated Influence of Culture

Men likely do not carry a gene responsible for the increased risk of dementia after the death of their wife. “In Japan and many other cultures, male life revolves around work. As a result, they rely heavily on the emotional and practical support of their partner,” explains study leader Koichiro Shiba in a statement from Boston University.3 Men may have had fewer opportunities to maintain social contacts and feel isolated after losing their partner. The scientist also has a hypothesis for the increased happiness of widows. “Japanese women are much more often the primary caregivers for their partners. When this burden is removed, they have more time for themselves and their interests.”

Strengths and Weaknesses of the Study

With a total of 34,000 observations spread over three periods, this is the largest and most detailed study of its kind to date. Additionally, it goes particularly in-depth with its numerous questions. This is interesting because the topic of grief is still far too little researched, as the study authors emphasize. Previous studies have mainly focused on the impact on women, as they are more often affected due to their higher life expectancy.4 Important aspect: The answers are based on self-reports. In Japanese culture, it is rather uncommon to clearly express negative feelings. Therefore, distortions cannot be ruled out. And: Like any observational study, it cannot make statements about cause and effect. However, it once again highlights how traditional gender roles affect men’s health.

Also interesting: What is Broken Heart Syndrome?

More on the topic

What Needs to Be Researched Urgently Now

Despite some insightful findings, many questions remain unanswered. On the one hand, Japanese culture, its gender roles, and social systems differ significantly from Western ones. Therefore, it is unclear to what extent the results, which also only apply to older individuals, can be transferred and what role the relationship quality of individual couples plays. “Even though the vast majority is due to cultural and social causes, biological mechanisms could amplify the effect,” explains study leader Prof. Kenjiro Kawaguchi when asked by FITBOOK. “Grief-related stress can, for example, activate the HPA axis and increase inflammatory markers. Women and men react differently to this.” But further research is needed here as well.

Advice from the Study Leader to Affected Family Members

Despite enormous differences in health systems and norms, Kawaguchi believes the results are broadly transferable to Germany. “A German study also showed that men are more susceptible to developing depressive symptoms later.” One aspect can be universally derived: Like all people, men should not be left alone during emotionally painful phases. This means talking to them about feelings and actively supporting them in participating in social life. How can I specifically help my grieving grandfather or father? “The first year after a bereavement is a particularly critical phase. Support him in building a social network he can rely on. Keep in touch and ensure he regularly visits the doctor.” According to the scientist, the central message is that the death of a wife not only affects emotional life but can also seriously impact physical and cognitive health.

This article is a machine translation of the original German version of FITBOOK and has been reviewed for accuracy and quality by a native speaker. For feedback, please contact us at info@fitbook.de.

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